mitoxantrone
InChIKey: KKZJGLLVHKMTCM-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-4htiMA Cannabis (Cannabis sativa) Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study. BeWo: CBD-mitoxantrone In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone cannabidiol
NPDI-ZFfQJg Cannabis (Cannabis sativa) The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. Mitoxantrone-CBD In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone cannabidiol
NPDI-3LZeDA Cannabis (Cannabis sativa) The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. Mitoxantrone-THC In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone delta-9-tetrahydrocannabinol
NPDI-jCImIg Goldenseal (Hydrastis canadensis) Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2) BCRP inhibition measured by accumulation In Vitro Transporter Kinetics positive — In Vitro Transport
  • BCRP (ABCG2)
 mitoxantrone
NPDI-YlLZrw Goldenseal (Hydrastis canadensis) Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2) Inhibition of BCRP by Berberine In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone berberine
NPDI-3VIAiw Cannabis (Cannabis sativa) Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study. Jar: CBD-Mitoxantrone In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone cannabidiol
NPDI-dsHL7w Cannabis (Cannabis sativa) The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. Mitoxantrone-CBN In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • BCRP (ABCG2)
 mitoxantrone cannabinol
NPDI-GRyerw Cannabis (Cannabis sativa) Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study. MCF7/P-gp: CBD-mitoxantrone In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
 mitoxantrone cannabidiol

Compound information from external resources

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