Inhibition of BCRP by Berberine CSV JSON

In Vitro Transporter Inhibition Experiment

Inhibition of BCRP by Berberine

Inhibition was detected.  Cutoff used — not specified

mitoxantrone

berberine 19012197

  • BCRP (ABCG2)

Transfected / siRNA knock-out / injected cells HEK293 transfected cells

Results

Table 2 - significance not mentioned so assumed to be not significant

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Cell Culture Conditions

7 x 10^5 cells/mL

200 μg/mL

Assay Conditions

90 min

37 deg C

5 μM

50 μM

Sigma–Aldrich, Auckland, NZ