- Natural product: Cannabis (Cannabis sativa)
- Associated study: The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids.
In Vitro Transporter Inhibition Experiment
Mitoxantrone-CBD
Inhibition was detected. Cutoff used — Not specified
- BCRP (ABCG2)
Cell system Other cells
Results
Table 1 (MEF3.8/Bcrp 1 A2)
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
5 x 10^4 cells/well
24-well
0.75
60 min
37 deg C
20 μM
80 nM-50 μM