- Natural product: Cannabis (Cannabis sativa)
- Associated study: Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study.
In Vitro Transporter Inhibition Experiment
Jar: CBD-Mitoxantrone
Inhibition was detected. Cutoff used —
Not specified
- BCRP (ABCG2)
Cell system Jar
Results
Fig 1b at 25 μM CBD
10 μM CBD ~125% ± 10% inhibition
Table 1
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
15 x 10^4 - 20 x 10^4 cells/well
6-well plates
30 min pre-, 30 min post
7.4
10 and 25 μM
The Hebrew University