Non-induction of CYP1A1 mRNA expression by 50 µM cannabinol CSV JSON

In Vitro Enzyme Induction Experiment

Non-induction of CYP1A1 mRNA expression by 50 µM cannabinol

Non-induction was detected.  Cutoff used —

"The significance of differences between the means of the various groups was evaluated by means of a one-way analysis of variance followed by Bonferroni or Dunnett's post-hoc test."

cannabinol

  • CYP1A1 4173297

Cell system HepG2 cell line

Results

Estimated from Figure 2

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

mRNA expression

1000000 cells/well

Yes

0, 5, 10, 25, 50 µM

6 h

Platinum® SYBR® Green qPCR SuperMix-UDG qPCR (Invitrogen)