- Natural product: Goldenseal (Hydrastis canadensis)
- Associated study: Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine
In Vitro Transporter Kinetics Experiment
Transport of Berberine by OAT1B3
Transport Activity was detected. Cutoff used — not specified
berberine 19012197
- OATP1B3 (SLCO1B3)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
Results
Fig 5 p value compared to mock control
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
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Experimental Conditions
1.5 x 10^5
12 well
15 min
37 deg C
10 μM