In Vitro Transporter Kinetics Experiment

P-gp Transport of Berberine

Transport Activity was detected.  Cutoff used — not specified

Berberine 19012197

  • P-gp (ABCB1)

Transfected / siRNA knock-out / injected cells MDCK transfected cells

Results

Fig 6b estimate at 60 min

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Cell Culture Conditions

1 x 10^8 cm^2

12 well

Cellstar or Thincert

2-4

Assay Conditions

60 min

37 deg C

7.4

25 μM