In Vitro Enzyme Inhibition Experiment

pHLM: CBN-warfarin

Inhibition was detected.  Cutoff used — Not specified


cannabinol (cbn)


  • CYP2C9 4309227

Cell fraction Pooled human liver microsomes -7999662


Tables 2, 3, and 4.
IC50 pre-incubation recorded at 20 min

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Commercially available

20 min

NADPH regenerating system

5 min

NADPH with precipitant