- Natural product: Goldenseal (Hydrastis canadensis)
- Associated study: Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine
In Vitro Transporter Kinetics Experiment
BBR-OATP1B1
No Transport Activity was detected. Cutoff used — not specified
berberine 19012197
- OATP1B1 (SLCO1B1)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
Results
Fig 5 - presented as concentration of BBR - in 1B1 there was no difference between control and transfected (thus 1 fold ratio)
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
1.5 x 10^5
12 well
15 min
37 deg C
10 μM