Zidovudine Glucoridination Kinetics in Rat Liver Microsomes With BSA CSV JSON

Zidovudine Glucoridination Kinetics in Rat Liver Microsomes With BSA

Object compound

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Rat liver microsomes

Table 4 - RLM With 1% BSA

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

With 1% bovine serum albumin (BSA)

Method for determination of overall effect

Metabolite formation study

Protein concentration

6 mg/mL

Test system preparation

In-house preparation

Incubation time

90 min

Protein linearity

Available

Time linearity

Available

Object concentrations tested

0 - 6 mM

NOTE