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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-C7Expw zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Inhibition of Mitragynine on ZDV Glucoronidation in RLM In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT2B7
zidovudine zidovudine glucuronide mitragynine
NPDI-xu0IJQ zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Zidovudine Glucoridination Kinetics in Human Liver Microsomes Without BSA In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT2B7
zidovudine zidovudine glucuronide
NPDI-Az8-Ow zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Inhibition of Mitragynine on ZDV Glucoronidation in HLM In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT2B7
zidovudine zidovudine glucuronide mitragynine
NPDI-msAUiw zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Zidovudine Glucoridination Kinetics in Rat Liver Microsomes With BSA In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT2B7
zidovudine zidovudine glucuronide
NPDI-dNsfLA zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Zidovudine Glucoridination Kinetics in Rat Liver Microsomes Without BSA In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT2B7
zidovudine zidovudine glucuronide
NPDI-7o9w1Q zidovudine Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents Zidovudine Glucoridination Kinetics in Human Liver Microsomes With BSA In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT2B7
zidovudine zidovudine glucuronide

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