- Compound: zidovudine
- Associated study: Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents
In Vitro Enzyme Inhibition Experiment
Inhibition of Mitragynine on ZDV Glucoronidation in HLM
Inhibition was detected. Cutoff used —
50% inhibition at concentration below 100 µM
- UGT2B7
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
1, 10, 100 µM