Inhibition of Mitragynine on ZDV Glucoronidation in RLM CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of Mitragynine on ZDV Glucoronidation in RLM

Inhibition was detected.  Cutoff used —

50% inhibition at concentration below 100 µM

zidovudine

mitragynine

zidovudine glucuronide

  • UGT2B7

Cell fraction Rat liver microsomes

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

1, 10, 100 ┬ÁM