Percent inhibition of CYP1A1 by (-)-epicatechin CSV JSON

In Vitro Enzyme Inhibition Experiment

Percent inhibition of CYP1A1 by (-)-epicatechin

Negligible Inhibition was detected.  Cutoff used — not provided



coumarin 19008106

  • CYP1A1 4173297

Recombinant expression system Not available
Cytochrome B5 Not available


Percent inhibition at 100 µM as estimated from Fig. 3 is presented.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.

CYP: 20 pmol/mL

In-house preparation

0.5 mL

15 min

NADPH regenerating system

Not available

Not available

10 µM

0-100 µM