Weak Inhibition of Corynantheidine for CYP3A4/5 CSV JSON

Weak Inhibition of Corynantheidine for CYP3A4/5

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

% result estimated from Figure 3 at around 100 µM

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

0.1 mg/ml

Incubation volume

200 µL

Incubation time

5 min

Co-factors

NADPH

Object concentrations tested

100 µM

Precipitant concentrations tested

1 - 100 µM

NOTE