Inhibition of 8-beta-hydroxylation of delta-9-THC by ketoconazole CSV JSON

Inhibition of 8-beta-hydroxylation of delta-9-THC by ketoconazole

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Table 1

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

10 microG

Test system preparation

Commercially available

Incubation time

20 min

Co-factors

NADPH
NADPH regenerating system

Object concentrations tested

64 µM

Precipitant concentrations tested

10 µM

NOTE