CYP2C19 Inhibition by Berberine CSV JSON

In Vitro Enzyme Inhibition Experiment

CYP2C19 Inhibition by Berberine

Negligible Inhibition was detected.  Cutoff used — TDI ≥1.5 fold decrease compared to preincubation

dibenzylfluorescein

berberine 19012197

fluorescein

  • CYP2C19 4311137

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Co-expressed

Results

Table 1

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

1.5 pmol

Commercially available

NADPH regenerating system

1 μM

30 min

NADPH with precipitant