Negligible inhibition of ABCC1 by THC CSV JSON

In Vitro Transporter Inhibition Experiment

Negligible inhibition of ABCC1 by THC

Non-inhibition was detected.  Cutoff used —

Not provided. A common convention is that IC50 > 100 micM signals negligible inhibition


  • ABCC1

Cell system Human ovarian carcinoma cell line


Measurements show 50% reduction in transport using increase in intracellular accumulation based on % of parent concentration.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

incubation time with two phases, cells and natural products for 30 min and then with Vincristine for another 90 min

Cell Culture Conditions

24 well plates

Assay Conditions

90 min

37 C

1 µg/ml

2, 10, 50, 100 and 200 µM