2D6 Inhibition by (+) Hydrastine CSV JSON

2D6 Inhibition by (+) Hydrastine

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Fig 4b (+) hydrastine at 1000 μM

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

1 mg/mL

Test system preparation

Commercially available

Incubation time

30 min

Co-factors

NADPH

Object concentrations tested

25 μ􏱂M

Precipitant pre-incubation condition

No NADPH with precipitant

Precipitant concentrations tested

10, 100, and 1,000 μ􏱂M

NOTE