2D6 Inhibition by (+) Hydrastine CSV JSON

In Vitro Enzyme Inhibition Experiment

2D6 Inhibition by (+) Hydrastine

Inhibition was detected.  Cutoff used — not specified

bufuralol

hydrastine

1'-hydroxybufuralol

  • CYP2D6 4173631

Cell fraction Pooled human liver microsomes -7999662

Results

Fig 4b (+) hydrastine at 1000 μM

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

1 mg/mL

Commercially available

30 min

NADPH

25 μ􏱂M

No NADPH with precipitant

10, 100, and 1,000 μ􏱂M