In Vitro Transporter Induction Experiment

THC

Induction was detected.  Cutoff used — Not specified

delta-9-tetrahydrocannabinol

  • P-gp (ABCB1)

Cell system Other cells

CEM/VLB100 cell-line used

Results

Emax: Fig 1a. Reported at 4 h.
Change from vehicle control: Estimated from Fig 1c. Reported at 4 h.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

mRNA expression

10^7 cells/mL

10 μM

Sigma-Aldrich

4, 8, 48 h

Rhodomine 123 uptake/retention assay