2C19 Inhibition by Hydrastine CSV JSON

2C19 Inhibition by Hydrastine

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Estimate from Fig 1 at 20 μM

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Test system preparation

In-house preparation

Test system lot number

HHM-247 and HHM-258

Incubation time

15 min

Co-factors

NADPH

Precipitant pre-incubation time

10 min

Precipitant pre-incubation condition

No NADPH with precipitant

Precipitant concentrations tested

1 or 20 μM

NOTE