Inhibition of CYP2C19 by Cannabidiol CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP2C19 by Cannabidiol

Inhibition was detected.  Cutoff used —

N/A

mephenytoin, (s)-

cannabidiol

4-hydroxymephenytoin, (s)-

  • CYP2C19 4311137

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

50 µg

250 µL

20 min

NADH

60 µM