- Natural product: Cannabis (Cannabis sativa)
- Associated study: Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19.
In Vitro Enzyme Inhibition Experiment
Inhibition of CYP2C19 by Cannabidiol
Inhibition was detected. Cutoff used —
N/A
- CYP2C19 4311137
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
50 µg
250 µL
20 min
NADH
60 µM