Inhibition of CYP3A by (-)-Epigallocatechin Gallate in HIM (Ki Determination) CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP3A by (-)-Epigallocatechin Gallate in HIM (Ki Determination)

Inhibition was detected.  Cutoff used — Ki determination

midazolam 708298

1'-hydroxymidazolam

  • CYP3A4 4306811

Cell fraction Pooled human intestinal microsomes -7999663

Results

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

Commercially available

100 µL

5 min

NADPH

Not available

Not available

0.8-3.4 µM

1-218 µM