In Vitro Transporter Inhibition Experiment
Inhibition was detected. Cutoff used — "The mean accumulation index had to be significantly > 1 (p < 0.05) to assess transporter inhibition potency by flow cytometry (n = 3 minimum)."
- P-gp (ABCB1)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
PSC833 5 μM was used as a positive control
|Sample||Compound measured||Value||Measurement||Study sequence||Additional information||N replicates|