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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-mLsAbQ Cannabis (Cannabis sativa) Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. Inhibition of P-gp by Cannabidiol 25 µM In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabidiol
NPDI-E56YVg Kratom (Mitragyna speciosa) P-glycoprotein interactions of novel psychoactive substances – Stimulation of ATP consumption and transport across Caco-2 monolayers Mitragynine Inhibition In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
rhodamine 123 mitragynine
NPDI-S4_OQA Cannabis (Cannabis sativa) Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2). Rh-123-THC In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
rhodamine 123 delta-9-tetrahydrocannabinol
NPDI-pvvgAw Cannabis (Cannabis sativa) Characterization of P-glycoprotein Inhibition by Major Cannabinoids from Marijuana CBD-Rh123 (Flow-Cytometry Assay) In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabidiol
NPDI-G8_czw Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CEM/VLB100: CBN In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabinol
NPDI-EqzxjQ Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CCRF-CEM: CBN In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabinol
NPDI-gOdMHw Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CCRF-CEM: CBD In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabidiol
NPDI-8Ej-Bg Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CCRF-CEM: THC In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 delta-9-tetrahydrocannabinol
NPDI-UIHjqQ Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CEM/VLB100: CBD In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 cannabidiol
NPDI-NC4pjQ Cannabis (Cannabis sativa) The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. CEM/VLB100: THC In Vitro Transporter Inhibition negative — In Vitro Transporter Non-inhibition
  • P-gp (ABCB1)
rhodamine 123 delta-9-tetrahydrocannabinol
NPDI-vs2diA Kratom (Mitragyna speciosa) P-glycoprotein interactions of novel psychoactive substances – Stimulation of ATP consumption and transport across Caco-2 monolayers R123 Transport Substrate In Vitro Transporter Kinetics positive — In Vitro Transport
  • P-gp (ABCB1)
rhodamine 123

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