- Natural product: Goldenseal (Hydrastis canadensis)
- Associated study: Effects of Herbal Products and their Constituents on Human Cytochrome P4502E1 Activity
In Vitro Enzyme Inhibition Experiment
CYP2E1 Inhibition by Berberine
Inhibition was detected. Cutoff used — not specified
- CYP2E1 4173608
Cell fraction Pooled human liver microsomes -7999662
Results
Table 3
n and significance not indicated
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
0.5 mL
NADPH
0.020 mM
20 min
NADPH with precipitant
4.0 μM