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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-NNibEQ Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2E1 Inhibition by Hydrastine In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
p-nitrophenol 4-nitrophenyl sulfate hydrastine
NPDI-aGqWbw Goldenseal (Hydrastis canadensis) Effects of Herbal Products and their Constituents on Human Cytochrome P4502E1 Activity 2E1 Inhibition by Hydrastine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2E1
p-nitrophenol 4-nitrophenyl sulfate hydrastine
NPDI-jjfDSA Goldenseal (Hydrastis canadensis) Effects of Herbal Products and their Constituents on Human Cytochrome P4502E1 Activity CYP2E1 Inhibition by GS root extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2E1
p-nitrophenol 4-nitrophenyl sulfate goldenseal root extract
NPDI-Wkqo4w Goldenseal (Hydrastis canadensis) Effects of Herbal Products and their Constituents on Human Cytochrome P4502E1 Activity CYP2E1 Inhibition by Berberine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2E1
p-nitrophenol 4-nitrophenyl sulfate berberine
NPDI-ij84RA Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2E1 Inhibition by Berberine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2E1
p-nitrophenol 4-nitrophenyl sulfate berberine
NPDI-mLlCzw Green tea (Camellia sinensis) Inhibitory effects of various beverages on ritodrine sulfation by recombinant human sulfotransferase isoforms SULT1A1 and SULT1A3 Green tea inhibition of SULT1A1 using 4-nitrophenyl as the substrate In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • SULT1A1
p-nitrophenol 4-nitrophenyl sulfate green tea leaf

Compound information from external resources

Resource Identifier
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