2E1 Inhibition by Hydrastine CSV JSON

In Vitro Enzyme Inhibition Experiment

2E1 Inhibition by Hydrastine

Inhibition was detected.  Cutoff used — not specified

p-nitrophenol

hydrastine

4-Nitrophenyl sulfate

  • CYP2E1 4173608

Cell fraction Pooled human liver microsomes -7999662

"hydrastine being most potent [inhibitor]"

Results

Table 3
n and significance not indicated

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

0.5 mL

NADPH

0.020 mM

20 min

NADPH with precipitant

4.0 μM