- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibitory effects of various beverages on ritodrine sulfation by recombinant human sulfotransferase isoforms SULT1A1 and SULT1A3
In Vitro Enzyme Inhibition Experiment
Green tea inhibition of SULT1A1 using 4-nitrophenyl as the substrate
Inhibition was detected. Cutoff used — Not available
- SULT1A1
Recombinant expression system E.coli
Cytochrome B5 No
Results
The above results were observed at concentrations of 5 and 10%. At green tea 1%, p-nitrophenol sulfation was significantly inhibited by approximately 90% (estimated from Fig. 4A; P < 0.01).
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
In-house preparation
50 µL
10 min (pH 6.8)
PAPS
1 µM
1, 5, and 10%