- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibitory effects of various beverages on ritodrine sulfation by recombinant human sulfotransferase isoforms SULT1A1 and SULT1A3
In Vitro Enzyme Inhibition Experiment
Green tea inhibition of SULT1A1 using 4-nitrophenyl as the substrate
Inhibition was detected. Cutoff used — Not available
- SULT1A1
                                            Recombinant expression system  E.coli
                                            
                                            
                                                
                                                Cytochrome B5  No
                                                
                                            
                                        
Results
The above results were observed at concentrations of 5 and 10%. At green tea 1%, p-nitrophenol sulfation was significantly inhibited by approximately 90% (estimated from Fig. 4A; P < 0.01).
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates | 
|---|
Experimental Conditions
                                                            
                                                                In-house preparation
                                                                
                                                                
                                                            
                                                        
50 µL
10 min (pH 6.8)
                                                            
                                                                PAPS
                                                                
                                                                
                                                            
                                                        
1 µM
1, 5, and 10%
