- Natural product: Licorice (Glycyrrhiza uralensis)
- Associated study: Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents
In Vitro Enzyme Inhibition Experiment
Negligible inhibition of CYP3A4 by G. uralensis Licorice extract
Negligible Inhibition was detected. Cutoff used —
> 100 µg/mL
- CYP3A4 4306811
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
0.2 mg/mL
10 min
NADPH
2.5 µM
11 concentrations from 0.005–250 μg/mL