- Natural product: Green tea (Camellia sinensis)
- Associated study: Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects.
In Vitro Transporter Inhibition Experiment
OATP1A2 inhibition with green tea
Inhibition was detected. Cutoff used — Not provided
nadolol 1313200
- OATP1A2 (SLCO1A2)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
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Experimental Conditions
poly-D-lysine hydrobromide-coated 12-well plates
2
5 min
37 deg C
7.3
100 µM
0.1 - 10% (10:100 dilution of green tea)
commercial green tea beverage (Healthya; Kao, Tokyo, Japan)