Inhibition of CYP3A4 by G. inflata Licorice extract CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP3A4 by G. inflata Licorice extract

Inhibition was detected.  Cutoff used —

> 100 µg/mL

midazolam 708298

1'-hydroxymidazolam

  • CYP3A4 4306811

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

10 min

NADPH

2.5 µM

11 concentrations from 0.005–250 μg/mL