In Vitro Enzyme Inhibition Experiment

HLM-CBN

Negligible Inhibition was detected.  Cutoff used — Not specified

diltiazem

cannabinol (cbn)

n-demethyldiltiazem

  • CYP3A

Cell fraction Individual human liver microsomes

Results

Table 2

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

50 μg

Commercially available

200 μL

15 min

MgCl2
NADPH regenerating system

50 μM

NADPH with precipitant

0-50 μM