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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-8vislA Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. CYP3A4-THC In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A4
diltiazem n-demethyldiltiazem delta-9-tetrahydrocannabinol (thc)
NPDI-FmAizA Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. CYP3A4-CBD In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
diltiazem n-demethyldiltiazem cannabidiol (cbd)
NPDI-ens_Gw Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. CYP3A4-CBN In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A4
diltiazem n-demethyldiltiazem cannabinol (cbn)
NPDI-PS8_LQ Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. HLM-THC In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A
diltiazem n-demethyldiltiazem delta-9-tetrahydrocannabinol (thc)
NPDI-zkYApA Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. HLM-CBD In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A
diltiazem n-demethyldiltiazem cannabidiol (cbd)
NPDI-yszOMw Cannabis (Cannabis sativa) Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety. HLM-CBN In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A
diltiazem n-demethyldiltiazem cannabinol (cbn)

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