- Natural product: Cannabis (Cannabis sativa)
- Associated study: Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: role of phenolic hydroxyl groups in the resorcinol moiety.
In Vitro Enzyme Inhibition Experiment
HLM-CBD
Inhibition was detected. Cutoff used — Not specified
- CYP3A
Cell fraction Individual human liver microsomes
Results
Table 2, Table 3
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
50 μg
Commercially available
200 μL
15 min
MgCl2
NADPH regenerating system
50 μM
NADPH with precipitant
0-50 μM