nicotine
InChIKey: SNICXCGAKADSCV-JTQLQIEISA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-94wcMQ Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by trans-cinnamic aldehyde (Model 1) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine trans-cinnamic aldehyde
NPDI-cowZsg Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by trans-cinnamic aldehyde (Model 2) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine trans-cinnamic aldehyde
NPDI-BawDOA Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by trans-cinnamic aldehyde (Model 3) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine trans-cinnamic aldehyde
NPDI-isPUmQ Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by 2-methoxycinnamaldehyde (Model 1) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine 2-methoxycinnamaldehyde
NPDI-kBkbaw Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by 2-methoxycinnamaldehyde (Model 2) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine 2-methoxycinnamaldehyde
NPDI-Uh2rZw Ceylon cinnamon (Cinnamomum verum) Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde Evaluation of Time Dependent Inhibition of CYP2A6 by 2-methoxycinnamaldehyde (Model 3) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
nicotine cotinine 2-methoxycinnamaldehyde

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