3A4/5 Inhibition by Hydrastine (PB) CSV JSON

3A4/5 Inhibition by Hydrastine (PB)

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Inhibition from Fig 6 (300 μM)
Fig 4a. (in parentheses)

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

0.2 mg/ml

Incubation volume

80 μl

Incubation time

10 min

Co-factors

NADPH regenerating system

Object concentrations tested

10 μM

Precipitant pre-incubation time

10 min

Precipitant concentrations tested

3, 10, 30, 100, 300 μM

NOTE