3A4/5 Inhibition by Berberine (PB) CSV JSON

3A4/5 Inhibition by Berberine (PB)

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Figure 4b (in parentheses)
Inhibition from Fig 6 (1000 μM)

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

0.2 mg/ml

Incubation volume

80 μl

Incubation time

10 min

Co-factors

NADPH regenerating system

Object concentrations tested

10 μM

Precipitant pre-incubation time

10 min

Precipitant concentrations tested

30, 100, 300, 600, 1000 μM

NOTE