3A4 Inhibition by Hydrastine (MDZ) CSV JSON

3A4 Inhibition by Hydrastine (MDZ)

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

Fig 1 Estimate at 20 μM

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Test system preparation

In-house preparation

Test system lot number

HHM-247 and HHM-258

Incubation time

15 min

Co-factors

NADPH

Precipitant pre-incubation time

10 min

Precipitant pre-incubation condition

No NADPH with precipitant

Precipitant concentrations tested

1 or 20 μM

NOTE