Gou Teng (Uncaria rhynchophylla)

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Latin Binomial: Uncaria rhynchophylla
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Natural Product Information From GSRS

Resource Identifier
= Induction
= Inhibition
= No overall effect

Published in vitro enzyme experiments

gou teng extract rhynchophylline isocorynoxeine isorhynchophylline corynoxeine
CYP3A4
ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-FsyoWg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-mNNsbA Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/5000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction negative — In Vitro Nuclear Receptor Non-induction
  • CYP3A4
gou teng extract
NPDI-yLL5dw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction negative — In Vitro Nuclear Receptor Non-induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-boTo-Q Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-TIcCbg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/250 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-Jo6i8g Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-jQcPOw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/50 Extracts on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
gou teng extract
NPDI-vUVs_g Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/2500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-2MTmoQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/1000 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-jhBFQw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-oFo-ZQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
gou teng extract
NPDI-cyF5-w Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/500 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-lVB-wQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/250 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-irr70Q Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/100 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-sfIKSQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Gou Teng 1/50 Extracts on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam gou teng extract
NPDI-r2D5-A Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isocorynoxeine Effect on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
isocorynoxeine
NPDI-ijtj8A Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Rhynchophylline Effect on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
rhynchophylline
NPDI-TWgdHQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isorhynchophylline Effect on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
isorhynchophylline
NPDI-kiJEYw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Corynoxeine Effect on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
corynoxeine
NPDI-ykk5HA Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isocorynoxeine Effect on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
isocorynoxeine
NPDI-1MMr9g Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Rhynchophylline Effect on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
rhynchophylline
NPDI-JIH7Lg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isorhynchophylline Effect on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
isorhynchophylline
NPDI-8GYr1A Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Corynoxeine Effect on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
corynoxeine
NPDI-VZwgtA Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Rhynchophylline on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam rhynchophylline
NPDI-jUInZg Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isocorynoxeine on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam isocorynoxeine
NPDI-3oSxuQ Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Isorhynchophylline on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam isorhynchophylline
NPDI-D-IVFw Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Corynoxeine on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam corynoxeine
NPDI-NH3c6A Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) Metabolomic Profiling of Gou Teng Extracts Characterization of Material