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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-H8eoWA Green Tea (Camellia sinensis) Effects of repeated green tea catechin administration on human cytochrome P450 activity. In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP2C9
losartan green tea leaf
NPDI-M8kbsQ Goldenseal (Hydrastis canadensis) Repeated administration of berberine inhibits cytochromes P450 in humans CYP2C9 Experiment In Vivo Interaction positive — PK Interaction - Increased systemic exposure
  • CYP2C9
losartan berberine