mitraphylline
InChIKey: JMIAZDVHNCCPDM-DAFCLMLCSA-N

Need public description.

Compound information managed by NaPDI

  • Kratom (Mitragyna speciosa)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-2HCqSQ Kratom (Mitragyna speciosa) Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline Mitraphylline p-gp transport kinetics MDCK In Vitro Transporter Kinetics positive — In Vitro Transport
  • P-gp (ABCB1)
 mitraphylline
NPDI-ruor3g Kratom (Mitragyna speciosa) Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline Mitraphylline P-gp transport kinetics In Vitro Transporter Kinetics positive — In Vitro Transport
  • P-gp (ABCB1)
 mitraphylline
NPDI-McqRuA Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Mitraphylline on CYP3A4 Activity In Vitro Enzyme Induction positive — In Vitro Enzyme Induction
  • CYP3A4
midazolam 1'-hydroxymidazolam mitraphylline
NPDI-t1K-qQ Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Mitraphylline Effect on CYP3A4 mRNA Expression In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • CYP3A4
mitraphylline
NPDI-h2rgNA Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) Mitraphylline Effect on PXR Activation In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
mitraphylline

Compound information from external resources

Resource Identifier
Google search JMIAZDVHNCCPDM-DAFCLMLCSA-N