paclitaxel
InChIKey: RCINICONZNJXQF-MZXODVADSA-N

Need public description.

Compound information managed by NaPDI


None listed

None listed

None listed

ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-37V97Q Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2C8 Inhibition by Aq GS Extract In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
paclitaxel 6-alpha-hydroxy paclitaxel aqueous goldenseal extract
NPDI-cesmqQ Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2C8 Inhibition by Ethanolic GS Extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
paclitaxel 6-alpha-hydroxy paclitaxel ethanolic goldenseal extract
NPDI-2kECKw Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2C8 Inhibition by Berberine In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
paclitaxel 6-alpha-hydroxy paclitaxel berberine
NPDI-VqNO0Q Goldenseal (Hydrastis canadensis) An in vitro Evaluation of Cytochrome P450 Inhibition and P-Glycoprotein Interaction with Goldenseal, Ginkgo biloba, Grape Seed, Milk Thistle, and Ginseng Extracts and Their Constituents 2C8 Inhibition by Hydrastine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
paclitaxel 6-alpha-hydroxy paclitaxel hydrastine

Compound information from external resources

Resource Identifier
Google search RCINICONZNJXQF-MZXODVADSA-N