raloxifene 6-glucuronide
InChIKey: MZPMSLSINDGEPM-WKRHDJAJSA-N

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-yWS4NQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1 and 1A8 by Nicardipine (Positive Control; Screening) In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A8
raloxifene raloxifene 6-glucuronide nicardipine
NPDI-rX0CIg Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epigallocatechin Gallate (Screening) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide (-)-epigallocatechin gallate
NPDI-Hzxkxw Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epicatechin Gallate (Screening) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide epicatechin gallate
NPDI-VlvwrQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epicatechin (Screening) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide (-)-epicatechin
NPDI-ubCatg Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (+)-catechin (Screening) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide catechin
NPDI-m23CAQ Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epigallocatechin (Screening) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide (-)-epigallocatechin
NPDI-8CdNjg Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epigallocatechin Gallate (Ki determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide (-)-epigallocatechin gallate
NPDI-WIQ_6A Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1, 1A8, and 1A10 by (-)-Epicatechin Gallate (Ki determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A10
  • UGT1A8
raloxifene raloxifene 6-glucuronide epicatechin gallate
NPDI-jljbXg Green tea (Camellia sinensis) Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation Inhibition of UGT1A1 and 1A8 by Green Tea Leaf Extract (T21) (Ki determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
  • UGT1A8
raloxifene raloxifene 6-glucuronide green tea leaf extract

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