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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-oZGcUg Cannabis (Cannabis sativa) Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. Inhibition of P-gp by Cannabidiol 25 µM In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
calcein-am cannabidiol
NPDI-IoxesQ Cannabis (Cannabis sativa) Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. Inhibition of P-gp by Cannabidiol 10 µM In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
calcein-am cannabidiol
NPDI-mJ7zbw Kratom (Mitragyna speciosa) Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline Inhibition of P-gp by Mitragynine In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
calcein-am mitragynine
NPDI-_5ld1Q Kratom (Mitragyna speciosa) Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline 7-Hydroxymitragynine P-gp Inhibition In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
calcein-am 7-hydroxymitragynine
NPDI-LCPweA Cannabis (Cannabis sativa) Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2). Calcein-AM-THC In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
calcein-am delta-9-tetrahydrocannabinol

Compound information from external resources

Resource Identifier
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